Strategic Statement: Interviewers are not usually interested in specific stories, unless specifically asked for! Your response to this question could very well be mentioning the same three strengths that every candidate is claiming. Your job is to frame it in a way that makes your response stand-out. In a question that focuses on negative attributes, it shouldn’t hurt to use a bit of humor.
Sample Response: I work hard to make sure that I’ve done my homework and that my decisions are informed decisions. As a result, I don’t generally default to “thinking outside of the box” as an initial strategy. Although I am very creative, I don’t think that I consider myself a risk-taker. I am much more comfortable with the expected than I am with the unexpected. Thirdly, I suppose I have an continuing issue with humility, because I can’t think of a third weakness!